Why Won't Johnny Run Linux? - Problems with Commercial Applications
Hard to build universal apps

Compiling an app that can run anywhere is hard
Qt3? 4? Gtk1? 2? Fltk? WxWidgets? XUL?
glibc-2.2? 2.3.2? 2.3.3? 2.4?
gcc-2.95? 3.3? 3.4? 4.0? 4.1?
RPM? DEB? TGZ? Klik? Autopackage?

Even adding items to system menu is a challenge

LSB some relief, but no (or little) sound support yet